Without spacedesk connected, could you please open the Device Manager on your primary machine, just run devmgmt.msc then check underneath Human Interface Devices if you can find any touch screen device with error (usually it shows a yellow exclamation mark).
For further analysis, please also send us the diagnostic info of your primary machine.
Just run spacedesk Driver Console -> Diagnostics, then click “Save All Information” button (in case it shows a message box, just click No to proceed).
PS: Saving all information will take a few seconds, then please send us the whole folder which contains the diagnostic logs collected.
Please right-click the folder -> Send to -> Compressed (zipped) folder, then attach the *.zip file in your next reply.